| Alec Pierce | Indianapolis Colts | Out | Pierce (anke) received a second PRP injection in his left ankle this offseason, James Boyd of The Athletic reports. |
| Sauce Gardner | Indianapolis Colts | Questionable | Gardner (calf) missed practice Tuesday due to an illness, James Boyd of The Athletic reports. |
| Cameron Mitchell | Indianapolis Colts | Questionable | Mitchell (undisclosed) reverted to the Colts' reserve/injured list Tuesday after clearing waivers, per the NFL's transaction log. |
| Cole Van Lanen | Jacksonville Jaguars | Out | The Jaguars placed Van Lanen (knee) on the active/PUP list Sunday. |
| Jack Kiser | Jacksonville Jaguars | Questionable | Kiser (knee) was not present during Thursday's practice, Ryan O'Halloran of The Florida Times-Union reports. |
| Tank Dell | Houston Texans | Questionable | Dell (knee) participated in "full-team drills" Monday, Aaron Wilson of KPRC 2 Houston reports. |
| Jake Hansen | Houston Texans | Questionable | Hansen (ankle) is considered week-to-week, Jonathan M. Alexander of the Houston Chronicle reports. |
| Jamal Hill | Houston Texans | Questionable | Hill underwent a procedure to address a wrist ligament injury during the offseason, Aaron Wilson of KPRC 2 Houston reports. |
| E.J. Speed | Houston Texans | Out | Speed (quadriceps) remains without a firm timetable for return and is looking at an extended absence, Aaron Wilson of KPRC 2 Houston reports. |
| M.J. Stewart | Houston Texans | Out | Texans GM Nick Caserio said Wednesday that Stewart (quadriceps) could return during training camp, Aaron Wilson of KPRC 2 Houston reports. |